Amazon’s Prime Big Deal Days (aka October Prime Day 2025) is finally here. With thousands of impressive beauty deals kicking off, it can take a minute to find what’s truly worth putting in your cart. Luckily, we already did some heavy lifting and found 12 skin-care steals worth shouting about when it comes to reducing wrinkles, tightening loose skin, addressing “tech neck,” depuffing eye bags and more concerns tied to aging skin.
Whether you’re after a hydrating moisturizer to plump up dry skin, a gentle retinol that delivers all the benefits without irritation, or a facial-sculpting device your cheekbones will thank you for later, now’s your moment to get them all on sale before they go back to full price. Keep reading for our picks of the best skin care deals for mature skin to shop during the Amazon Prime Big Deal Days 2025.
Best Prime Day Skin Care Deals
Not only are the majority of our picks dermatologist recommended, but several are winners of this year’s NewBeauty Awards and Readers Choice Awards, including the top honors for Best Neck Cream, Favorite Skin-Care Device, Best Moisturizer for Fine Lines and more.
Retrinal 0.1 Intensive Multi-Corrective Cream
This dermatologist-recommended cream has antioxidants, retinaldehyde, niacinamide and hyaluronic acid to reduce wrinkles and increase skin firmness and radiance. (It’s also safe for sensitive skin types.)
Triple Firming Neck Cream
The 2025 NewBeauty Award winner for Best Neck Cream uses the brand’s breakthrough MicroDiPeptide229 to take skin-smoothing to the next level.
Retinol Correxion Line Smoothing Eye Cream
Whether you’re looking to depuff the eyes, brighten dark circles, improve skin firmness or smooth out wrinkles (or all of the above), this drugstore favorite targets all of your eye area concerns with help from pure RoC retinol.
Collagen Bank 15% Vitamin C Serum
Neutrogena’s Collagen Bank line offers collagen-building and now brightening benefits with this serum made of polyhydroxy acids and vitamin C to gently exfoliate skin, even tone and promote radiance.
AGE REVERSE+ Total Correct Serum
It’s this year’s Awards winner for Best Multitasking Serum for Aging Skin because it “addresses just about every aging-skin concern we have, including uneven texture and tone, laxity, dullness, fine lines and wrinkles, lack of firmness and dryness,” according to our editors.
ELASTIderm Lift Up & Sculpt Facial Moisturizer
Yet another award-winner to on sale for Prime Day is the Best Moisturizer for Fine Lines: Obagi ELASTIderm. “In clinical trials, this moisturizer provided visible improvement in fine lines after six weeks of use, while also firming up slack areas. It also scores big points in the hydration department,” explains our editor.
TRINITY+ Microcurrent Facial Device Kit
Our readers voted NuFace TRINITY+ their Favorite Skin-Care Device in this year’s Readers Choice Awards. The microcurrent power does it all, from lifting and contouring to smoothing and toning, all in the name of promoting a firmer, younger-looking complexion.
The Sculpt Arm Compound
Deemed an “anti-gravity cream” by the brand, this full-body formula is made with antioxidants, caffeine and retinol to firm and tighten sagging or crepey skin, especially on the arms, neck and décolleté.
Smart Clinical Repair Wrinkle Correcting Serum
Fragrance-free and allergy tested, this serum is a great pick for sensitive skin types who want to reduce wrinkles. With encapsulated retinol—a slower-releasing form of the active that minimizes the risk of irritation—its gently resurfaces skin and smoothes lines and texture. Other key ingredients include hydrating hyaluronic acid and skin-plumping peptides.
345 Relief Cream Mist
K-beauty brand Dr. Althea created this ultra-fine mist with a twist; it’s has dual layers of liquid and creamy textures. With three types of hyaluronic acid, centella asiatica leaf extract and panthenol, it replenishes dry skin with moisture and soothes any redness instantly, while leaving skin looking like glass and baby soft to the touch.
Clear Sunscreen Stick SPF 50+
The first line of defense against unwanted visible signs of again is SPF. SHISEIDO’s award-winning, clear sunscreen stick with broad-spectrum SPF 50+ can be re-applied anytime, anywhere, over or under makeup.
Mela B3 Serum
Acne marks, sun exposure and age spots are no match for La Roche-Posay’s Mela B3 Serum. With 10 percent niacinamide, expect visible skin brightening and a more even complexion overall.
When is Amazon Prime Big Deal Days 2025?
Prime Big Deal Days will take place on Tuesday, October 7, and Wednesday, October 8. The official start begins October 7 at 12:01 a.m. PDT and runs until midnight on October 8.
Who can shop Prime Big Deal Days?
To take full advantage of Prime Big Deal Days discounts, you have to be a Prime member. To sign up for a free, 30-day trial, click here.
