- Do start early if you want prevention, don’t wait for deep grooves.
- Do plan ahead, don’t expect instant results.
- Do expect pinches and bruises, don’t be surprised by discomfort.
- Do remember it’s temporary, don’t think you’re locked in.
- Do speak up if you’re nervous, don’t panic if you feel faint.
- Do lift your brows, don’t overload the forehead.
- Do know what neurotoxin is, don’t confuse it with filler.
- Do be consistent, don’t expect one session to erase deep lines.
- Do give yourself downtime, don’t jump back into workouts.
- Do invest in expertise, don’t go bargain hunting.
You’ve probably already heard some of the standard advice when it comes to getting neurotoxin injections: Skip alcohol for at least 24 hours before your appointment, avoid blood-thinning pain relievers and don’t bend your neck down to scroll on your phone afterward. But what else should you know before your first time using a wrinkle relaxer? We went straight to the experts to break down the key dos and don’ts, from what to expect during your appointment to how to time your treatment.
Do start early if you want prevention, don’t wait for deep grooves.
Fairfax, VA dermatologist Brenda Dintiman, MD says, “Botox and other neurotoxins used as ‘Pretox’ can soften your forehead lines in your 20s and 30s to prevent lines at rest.” In other words, you don’t need to wait until wrinkles are etched in. Light, early treatment can keep skin looking smoother over time.
She also notes another perk: “Neurotoxin injections along your hairline, front and back, can decrease sweating so your blowout will last longer even if you are exercising daily.” Men who are balding often benefit too, noticing less sweat running down the scalp and face.
Do plan ahead, don’t expect instant results.
Fort Lauderdale, FL dermatologist Dr. Matthew J. Elias says, “It can take up to two weeks to see results so don’t fret if you don’t see anything right away.” While you may notice subtle changes sooner, peak smoothing happens around two weeks. If you have a wedding, photoshoot or major event, give yourself a buffer.
Louisville, KY dermatologist Tami Buss Cassis, MD warns, “You might bruise and it can take a couple of weeks to kick in so don’t plan it right before a big event.”
Do expect pinches and bruises, don’t be surprised by discomfort.
Speaking of bruising—it’s possible. “This treatment is done with needles, so there is some discomfort. If you’re nervous or prone to fainting around needles, you may feel lightheaded, and bruising can occur,” says Dr. Daniel. While most people tolerate the quick pinches well, first-timers should be aware that mild bruising or tenderness is common.
Do remember it’s temporary, don’t think you’re locked in.
Northville, MI dermatologist Farhaad Riyaz, MD explains, “Botox typically lasts three to four months. If you don’t love it, it will wear off; if you do, you’ll know when to return.” Most neurotoxins, like Botox, Dysport, Xeomin and Jeuveau, last three to four months, while Daxxify may last longer. This is why it makes for a good first injectable—think of it as a beauty test-drive. You’re not committed forever.
Do speak up if you’re nervous, don’t panic if you feel faint.
“Feeling faint happens,” says Dr. Riyaz. Some first-timers experience a quick wave of dizziness, not because of the neurotoxin itself but from nerves or the needle. It passes quickly, but giving your provider a heads up ensures they can keep you comfortable.=
Do lift your brows, don’t overload the forehead.
New Orleans, LA dermatologist Mary Lupo, MD says, “Botox and all the similar products are best used to lift and flare the brows. Excessive dosages in the forehead can risk a brow drop.” A skilled injector will place neurotoxin strategically, so you look bright and refreshed, not heavy-lidded.
Do know what neurotoxin is, don’t confuse it with filler.
Sterling, VA dermatologist Stephanie Daniel, MD clarifies: “It is not filler. It does not fill spaces. It prevents motion where we are trying to prevent motion.” Filler restores lost volume while neurotoxin prevents muscles from creating wrinkles. Knowing the difference helps set the right expectations.
Do be consistent, don’t expect one session to erase deep lines.
“Especially for well-developed lines it can take multiple injections over a year to achieve the desired results,” says Dr. Daniel. Botox works best preventatively and for fine lines, but deeper grooves take time and consistency to soften.
Do give yourself downtime, don’t jump back into workouts.
Sweating and high activity right after injections can interfere with results. Dr. Riyaz advises skipping exercise until the next day to avoid the neurotoxin shifting. Consider it your excuse to swap spin class for a rest day.
Do invest in expertise, don’t go bargain hunting.
“Choose the injector, not the price,” says Dr. Riyaz. The precision of neurotoxin is what makes it beautiful—or risky. A board-certified dermatologist or plastic surgeon understands anatomy and knows how to deliver natural results. Cheaper deals might look appealing, but the outcome is only as good as the person holding the syringe.
