Prime Day 2025 is here, and some of the best deals aren’t on gadgets or home tech, they’re on dermatologist-approved skin-care staples. From multitasking sunscreens to soothing post-procedure creams, these are the products the experts actually use and recommend.
SkinMedica TNS Advanced+ Serum (originally $295, now $236)
“SkinMedica’s TNS serum includes peptides and proprietary ingredients that are clinically shown to improve the appearance of fine lines and wrinkles in just a few weeks,” says board-certified Randolph, NJ dermatologist Cindy Wassef, MD. “This is a great deal on a wonderful product.”
Colorescience Sunforgettable Total Protection Sport Stick SPF 50 (originally $39, now $32)
For board-certified Northville, MI dermatologist Farhaad Riyaz, MD this portable sunscreen is a daily essential. “I use the Colorescience Sunforgettable Total Protection Sport Stick every day—it’s perfect for outdoor workouts and long rides since it’s mineral, sweat-resistant and fits easily in a pocket without leaking or melting,” he says.
ISDIN Eryfotona Actinica Mineral Sunscreen SPF 50 (originally $73, now $51)
“This sunscreen represents how far we’ve come in merging daily protection with true skin repair,” says board-certified New York dermatologist Julie Russak, MD. “ISDIN Eryfotona Actinica isn’t just a broad-spectrum, 100 percent mineral SPF—it’s formulated with DNA Repairsomes that help the skin repair and reverse signs of sun damage while preventing new ones from forming.”
Alastin HydraTint Pro Mineral Sunscreen SPF 36 (originally $79, now $57)
“I love Alastin HydraTint Pro Mineral Sunscreen because it gives beautiful, lightweight coverage while protecting against UV damage,” says board-certified Miami dermatologist Dr. Deborah Longwill. “It’s hydrating, blends seamlessly into the skin, and gives that healthy, even-toned glow my patients love for everyday use.”
Differin Acne Treatment Kit (originally $28, now $23)
“I like the Differin Acne Skin Care Kit because it includes a lot of tried-and-true ingredients that work well for acne-prone skin, including adapalene and benzoyl peroxide,” says board-certified West Palm Beach, FL dermatologist Jacob Beer, MD. “It’s an affordable, effective starter regimen that covers all the basics.”
Dove Beauty Bar (originally $13, now $10)
For board-certified Houston dermatologist Jennifer Segal, MD, it’s best to keep it simple: “I don’t typically recommend buying high-end skin products on Amazon,” she says. “Maybe the Dove Beauty Bar.”
Anua PDRN 100 Moisturizing Cream (originally $24, now $17)
“I’m thrilled to share one of my favorite recent K-beauty discoveries: the Anua PDRN 100 Moisturizing Cream,” says board-certified New York dermatologist Elaine Kung, MD. “It’s wonderfully lightweight yet deeply hydrating, with PDRN for regeneration, hyaluronic acid for moisture, and centella asiatica and niacinamide to calm and strengthen the barrier.”
Vanicream Gentle Facial Cleanser (originally $13, now $7)
Board-certified Fort Lauderdale dermatologist Dr. Matthew Elias says one everyday essential to stock up on is Vanicream’s gentle cleanser. Known for being fragrance-free and ideal for sensitive skin, it’s a dermatologist-approved basic for healthy skin.
Supergoop! Unseen Sunscreen SPF 40 (originally $38, now $30)
“Supergoop works,” says board-certified New York dermatologist Orit Markowitz, MD. She notes it’s a reliable, effective sunscreen she recommends for daily use. It’s lightweight, easy to wear and a formula that actually makes people want to apply SPF every day.
Colorescience Sunforgettable Total Protection Face Shield Flex SPF 50 (originally $58, now $49)
“I like this sunscreen because it’s a lightweight, tinted mineral formula that instantly evens skin tone for a smooth, flawless finish,” says board-certfied New York dermatologist Marina Peredo, MD. “It’s hydrating, antioxidant-rich, and gives that perfect no-makeup glow with 100 percent mineral actives.”
Nutrafol Hair Serum (originally $49, now $39)
“Nutrafol! Even though we’d like to sell it from our website, it’s a good deal right now—so why not get started?” says board-cerftified Studio City, CA dermatologist Gene Rubinstein, MD. “Especially the serum. You can add it to your Nutrafol regimen or start with a topical treatment if you prefer no pills.”
Miracle Plus Arnica Cream Bruise Relief Lotion (originally $28, now $22)
“Bruising and swelling are common after aesthetic treatments and products with arnica can really help minimize those effects,” says board-certified Charlotte, NC dermatologist Gilly Munavalli, MD. This one combines arnica montana with vitamin K and horse chestnut to calm the skin and support faster recovery.
Clean Skin Club Healthy Aging Clean Towels
(originally $17, now $12)
“They’re super soft and don’t disrupt the skin barrier, which makes them ideal for anyone with sensitive skin, eczema, or rosacea,” says Washington, DC dermatologist Tina Alster, MD. “I use them with a gentle cleanser or makeup remover to cleanse and remove makeup every night.”
Neutrogena Purescreen+ Mineral UV Tint Face Liquid With Vitamin E SPF 30 (originally $19, now $12)
Delray Beach dermatologist Janet Allenby, MD says Neutrogena’s tinted mineral sunscreen is a “great Amazon buy.” With neutral undertones, broad-spectrum SPF protection and antioxidants, it’ll keep skin glowy and youthful.